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SHANK3 抗体 (AA 1055-1616)

SHANK3 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1742347
发货至: 中国
  • 抗原 See all SHANK3 抗体
    SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
    抗原表位
    • 15
    • 10
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1055-1616
    适用
    • 43
    • 10
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 25
    • 22
    克隆类型
    • 25
    • 22
    多克隆
    标记
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SHANK3 antibody is un-conjugated
    应用范围
    • 31
    • 27
    • 23
    • 21
    • 17
    • 13
    • 13
    • 10
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    特异性
    Specific for shank 3.
    纯化方法
    antiserum
    免疫原
    Recombinant protein (aa 1055-1616 of rat shank 3).
    Top Product
    Discover our top product SHANK3 Primary Antibody
  • 应用备注
    WB: 1 : 1000 (AP staining)
    IP: not tested yet
    ICC: 1 : 500
    IHC: 1 : 500
    说明

    IHC: For best results the antibody requires a mild fixation protocol (2 % PFA in sodium acetate buffer, pH 6).

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS
    注意事项
    Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
    Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.
    储存条件
    4 °C/-20 °C
    储存方法
    Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
  • Tao-Cheng, Toy, Winters, Reese, Dosemeci: "Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses." in: PLoS ONE, Vol. 11, Issue 5, pp. e0153979, (2016) (PubMed).

    Wei, Ma, Ding, Jin, Liu, Chang, Hu, Yu: "Reduced Glutamate Release in Adult BTBR Mouse Model of Autism Spectrum Disorder." in: Neurochemical research, Vol. 41, Issue 11, pp. 3129-3137, (2016) (PubMed).

    Wei, Ma, Liu, Ding, Jin, Wang, Hu, Yu: "Inhibition of IL-6 trans-signaling in the brain increases sociability in the BTBR mouse model of autism." in: Biochimica et biophysica acta, Vol. 1862, Issue 10, pp. 1918-25, (2016) (PubMed).

    Hagmeyer, Mangus, Boeckers, Grabrucker: "Effects of trace metal profiles characteristic for autism on synapses in cultured neurons." in: Neural plasticity, Vol. 2015, pp. 985083, (2015) (PubMed).

  • 抗原
    SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
    别名
    Shank 3 (SHANK3 产品)
    别名
    DEL22q13.3 antibody, PROSAP2 antibody, PSAP2 antibody, SCZD15 antibody, SPANK-2 antibody, Prosap2 antibody, AI841104 antibody, Shank3b antibody, SH3 and multiple ankyrin repeat domains 3 antibody, SH3 and multiple ankyrin repeat domains protein 3 antibody, SHANK3 antibody, shank3 antibody, Shank3 antibody
    背景
    Synonyms: ProSAP2, SPANK2
    途径
    Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity
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