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TP53BP1 抗体 (AA 574-773)

Cited in 2+ publications. This 小鼠 单克隆 anti-TP53BP1 antibody (Clone 6B3E10) specifically detects TP53BP1 in WB, IHC, ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1724820
发货至: 中国
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Quick Overview for TP53BP1 抗体 (AA 574-773) (ABIN1724820)

抗原

See all TP53BP1 抗体
TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TP53BP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

6B3E10
  • 抗原表位

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    AA 574-773

    原理

    TP53BP1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nakada, Yonamine, Matsuo: "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1." in: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012) (PubMed).

    Mok, Henderson: "The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 9, pp. 1398-409, (2012) (PubMed).

  • 抗原

    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

    别名

    TP53BP1

    背景

    T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis,enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage.

    分子量

    213.6 kDa

    基因ID

    7158

    UniProt

    Q12888

    途径

    DNA Damage Repair
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