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ITK 抗体 (AA 2-110)

Cited in 2+ publications. This 小鼠 单克隆 anti-ITK antibody (Clone 5G12C4) specifically detects ITK in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN1724708
发货至: 中国
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Quick Overview for ITK 抗体 (AA 2-110) (ABIN1724708)

抗原

See all ITK 抗体
ITK (IL2-Inducible T-Cell Kinase (ITK))

适用

  • 57
  • 20
  • 12
  • 6
  • 3

宿主

  • 71
  • 4
  • 2
小鼠

克隆类型

  • 62
  • 15
单克隆

标记

  • 32
  • 9
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ITK antibody is un-conjugated

应用范围

  • 50
  • 33
  • 23
  • 14
  • 14
  • 13
  • 7
  • 4
  • 4
  • 4
  • 3
  • 1
ELISA

克隆位点

5G12C4
  • 抗原表位

    • 10
    • 10
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-110

    原理

    ITK Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of ITK (aa2-110) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Graves, Siroux, Guerra, Klimecki, Martinez: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." in: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).

    Perez-Villar, ODay, Hewgill, Nadler, Kanner: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." in: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).

  • 抗原

    ITK (IL2-Inducible T-Cell Kinase (ITK))

    别名

    ITK

    背景

    ITK: IL2-inducible T-cell kinase. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

    UniProt

    Q08881

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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