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Survivin 抗体

This anti-Survivin antibody is a 小鼠 单克隆 antibody detecting Survivin in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724686
发货至: 中国

Quick Overview for Survivin 抗体 (ABIN1724686)

抗原

See all Survivin (BIRC5) 抗体
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

适用

  • 130
  • 58
  • 48
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 99
  • 41
  • 1
  • 1
小鼠

克隆类型

  • 94
  • 48
单克隆

标记

  • 81
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  • 4
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Survivin antibody is un-conjugated

应用范围

  • 111
  • 56
  • 45
  • 42
  • 26
  • 26
  • 24
  • 20
  • 14
  • 13
  • 7
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  • 5
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  • 1
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ELISA

克隆位点

2H5H2
  • 原理

    Survivin Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of Survivin expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Karam, Lotan, Ashfaq, Sagalowsky, Shariat: "Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder." in: Urology, Vol. 70, Issue 3, pp. 482-6, (2007) (PubMed).

    Piras, Murtas, Minerba, Ugalde, Floris, Maxia, Colombari, Perra, Sirigu: "Nuclear survivin is associated with disease recurrence and poor survival in patients with cutaneous malignant melanoma." in: Histopathology, Vol. 50, Issue 7, pp. 835-42, (2007) (PubMed).

  • 抗原

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    别名

    Survivin

    背景

    Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

    基因ID

    332

    UniProt

    O15392

    途径

    Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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