IL1A 抗体
Quick Overview for IL1A 抗体 (ABIN1724632)
抗原
See all IL1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IL-1a Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human IL1a expressed in E. Coli.
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亚型
- IgG2a
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism." in: Annals of neurology, Vol. 47, Issue 3, pp. 361-5, (2000) (PubMed).
: "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease." in: Neurology, Vol. 55, Issue 4, pp. 480-3, (2000) (PubMed).
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: "Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism." in: Annals of neurology, Vol. 47, Issue 3, pp. 361-5, (2000) (PubMed).
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- IL-1a
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背景
- Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease
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分子量
- 30.6 kDa
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基因ID
- 3552
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UniProt
- P01583
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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