MLLT1 抗体 (AA 414-472)
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- 抗原 See all MLLT1 抗体
- MLLT1 (MLLT1, super elongation complex subunit (MLLT1))
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抗原表位
- AA 414-472
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MLLT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Reacts with human ENL.
- 纯化方法
- Purified (protein G)
- 免疫原
- Maltose-binding fusion protein containing ENL amino acids 414-472 (Accession no. NP_005925).
- 克隆位点
- 3-1-1
- 亚型
- IgG1
- Top Product
- Discover our top product MLLT1 Primary Antibody
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anti-MLLT1, super elongation complex subunit (MLLT1) (AA 472-559) antibody
MLLT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3H2 unconjugated
anti-MLLT1, super elongation complex subunit (MLLT1) (AA 1-559) antibodyMLLT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-MLLT1, super elongation complex subunit (MLLT1) (AA 523-552), (C-Term) antibodyMLLT1 适用: 人 WB 宿主: 兔 Polyclonal RB1927-1928 unconjugated
anti-MLLT1, super elongation complex subunit (MLLT1) (Internal Region) antibodyMLLT1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-MLLT1, super elongation complex subunit (MLLT1) (AA 1-126) antibodyMLLT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MLLT1, super elongation complex subunit (MLLT1) (AA 357-406) antibodyMLLT1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB(1 - 5 μg/mL) - 限制
- 仅限研究用
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- 缓冲液
- PBS, pH 7.4.
- 注意事项
- Dilute in PBS or medium that is identical to that used in the assay system.
- 储存条件
- -20 °C
- 储存方法
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MLLT1 (MLLT1, super elongation complex subunit (MLLT1))
- 别名
- ENL (MLLT1 产品)
- 别名
- MGC84026 antibody, MLLT1 antibody, ENL antibody, LTG19 antibody, YEATS1 antibody, AA407901 antibody, BAM11 antibody, MLLT1, super elongation complex subunit antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 antibody, Mllt1 antibody, MLLT1 antibody, mllt1.L antibody, mllt1 antibody
- 背景
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The AF4 and ENL (Eleven nineteen Leukemia) protein families are the most frequent MLL fusion partners accounting for two-thirds of MLL-associated leukemia incidence. The ENL family includes ENL and AF9 and has structural homology to the yeast Anc1 protein. ENL is a nuclear protein that is capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells as well as in yeast. Deletion muta-genesis demonstrated that the minimal portion of ENL required for activation of transcription was localized to its C-terminal 90 amino acids. This region is highly conserved between ENL and AF9 and is retained in all Hrx-ENL and Hrx-AF9 fusion proteins. Thus, the leukemogenic contribution and transcriptional activation potential of ENL colocalize to its highly conserved carboxy terminus.
Protein ENL YEATS domain-containing protein 1 LTG19 YEATS1 Gene name : MLLT1 - 基因ID
- 4298
- UniProt
- Q03111
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