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ATM 抗体 (full length)

ATM 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, IP, FACS, ICC, ChIP 宿主: 小鼠 Monoclonal 2C1 unconjugated
产品编号 ABIN1721458
发货至: 中国
  • 抗原 See all ATM 抗体
    ATM (Ataxia Telangiectasia Mutated (ATM))
    抗原表位
    • 32
    • 16
    • 15
    • 13
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2577-3056, full length
    适用
    • 155
    • 80
    • 33
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 猴
    宿主
    • 135
    • 20
    • 6
    • 2
    小鼠
    克隆类型
    • 129
    • 34
    单克隆
    标记
    • 79
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This ATM antibody is un-conjugated
    应用范围
    • 72
    • 45
    • 39
    • 32
    • 28
    • 26
    • 21
    • 20
    • 18
    • 12
    • 8
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)
    特异性
    Reacts with human ATM. Cross-reacts with mouse, rat and monkey protein.
    纯化方法
    Purified
    免疫原
    GST fusion protein expressed in E. coli corresponding to aa 2577- 3056 of full-length ATM.
    克隆位点
    2C1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ATM Primary Antibody
  • 应用备注
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB1:500 - 1:3000 IHC-P5 μg/mL IP1 - 10 μg/mL.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.4
    注意事项
    Dilute in PBS or medium that is identical to that used in the assay system.
    储存条件
    -20 °C/-80 °C
    储存方法
    Stable for at least one year at -20°C or -70°C. Avoid multiple freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ATM (Ataxia Telangiectasia Mutated (ATM))
    别名
    ATM (ATM 产品)
    别名
    ATM antibody, Atm antibody, CG6535 antibody, Dmel\\CG6535 antibody, Tefu antibody, atm antibody, atm/tefu antibody, dATM antibody, tef antibody, Xatm antibody, at1 antibody, atdc antibody, tel1 antibody, telo1 antibody, AT1 antibody, ATA antibody, ATC antibody, ATD antibody, ATDC antibody, ATE antibody, TEL1 antibody, TELO1 antibody, AI256621 antibody, C030026E19Rik antibody, telomere fusion antibody, ATM serine/threonine kinase L homeolog antibody, ATM serine/threonine kinase antibody, ataxia telangiectasia mutated antibody, ataxia telangiectasia mutated (atm) antibody, serine/threonine-protein kinase ATM antibody, tefu antibody, atm.L antibody, atm antibody, ATM antibody, EDI_100660 antibody, CpipJ_CPIJ001772 antibody, BDBG_08252 antibody, PAAG_02532 antibody, MCYG_05088 antibody, VDBG_06833 antibody, ACLA_015700 antibody, LOC5565620 antibody, MGYG_07634 antibody, PGTG_14279 antibody, Atm antibody
    背景
    ATM is a 370 kD nuclear phosphoprotein,which is involved in the autooal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigations.

    Serine-protein kinase ATM Ataxia telangiectasia mutated, A-T mutated gene name: ATM AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
    基因ID
    472
    UniProt
    Q13315
    途径
    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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