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ATM 抗体 (full length)

This anti-ATM antibody is a 小鼠 单克隆 antibody detecting ATM in WB, IHC, ELISA, IF, IP, FACS, ICC 和 ChIP. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN1721458
发货至: 中国

Quick Overview for ATM 抗体 (full length) (ABIN1721458)

抗原

See all ATM 抗体
ATM (Ataxia Telangiectasia Mutated (ATM))

适用

  • 160
  • 69
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人, 小鼠, 大鼠, 猴

宿主

  • 134
  • 22
  • 5
  • 2
小鼠

克隆类型

  • 124
  • 39
单克隆

标记

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This ATM antibody is un-conjugated

应用范围

  • 76
  • 52
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  • 8
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)

克隆位点

2C1
  • 抗原表位

    • 33
    • 16
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    • 13
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    • 2
    • 1
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    • 1
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    • 1
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    • 1
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    AA 2577-3056, full length

    特异性

    Reacts with human ATM. Cross-reacts with mouse, rat and monkey protein.

    纯化方法

    Purified

    免疫原

    GST fusion protein expressed in E. coli corresponding to aa 2577- 3056 of full-length ATM.

    亚型

    IgG1 kappa
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB1:500 - 1:3000 IHC-P5 μg/mL IP1 - 10 μg/mL.

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.4

    注意事项

    Dilute in PBS or medium that is identical to that used in the assay system.

    储存条件

    -20 °C/-80 °C

    储存方法

    Stable for at least one year at -20°C or -70°C. Avoid multiple freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ATM (Ataxia Telangiectasia Mutated (ATM))

    别名

    ATM

    背景

    ATM is a 370 kD nuclear phosphoprotein,which is involved in the autooal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigations.

    Serine-protein kinase ATM Ataxia telangiectasia mutated, A-T mutated gene name: ATM AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1

    基因ID

    472

    UniProt

    Q13315

    途径

    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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