GLTSCR2 抗体 (AA 401-478)
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- 抗原 See all GLTSCR2 products
- GLTSCR2 (Glioma Tumor Suppressor Candidate Region Gene 2 (GLTSCR2))
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抗原表位
- AA 401-478
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLTSCR2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GLTSCR2/PICT1
- 亚型
- IgG
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anti-Glioma Tumor Suppressor Candidate Region Gene 2 (GLTSCR2) (AA 402-478) antibody
GLTSCR2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A8 unconjugated
anti-Glioma Tumor Suppressor Candidate Region Gene 2 (GLTSCR2) (AA 402-478) antibodyGLTSCR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glioma Tumor Suppressor Candidate Region Gene 2 (GLTSCR2) (AA 1-478) antibodyGLTSCR2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- GLTSCR2 (Glioma Tumor Suppressor Candidate Region Gene 2 (GLTSCR2))
- 别名
- GLTSCR2/PICT1 (GLTSCR2 产品)
- 别名
- GLTSCR2 antibody, pict1 antibody, pict-1 antibody, MGC115044 antibody, PICT-1 antibody, PICT1 antibody, 5330430H08Rik antibody, 9430097C02Rik antibody, AU041936 antibody, AW536441 antibody, R74911 antibody, NOP53 ribosome biogenesis factor antibody, NOP53 ribosome biogenesis factor L homeolog antibody, Nop53 antibody, NOP53 antibody, nop53 antibody, nop53.L antibody
- 背景
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Synonyms: Glioma tumor suppressor candidate region gene 2 protein, GLTSCR2, GSCR2_HUMAN, p60, PICT1, protein interacting with carboxyl terminus 1.
Background: The tumor suppressor PTEN plays an essential role in regulating signaling pathways involved in cell growth and apoptosis and is inactivated in a wide variety of tumors. Protein interacting with PTEN carboxyl terminus 1 (PICT-1), also designated p60 or Glioma tumor suppressor candidate region gene 2 protein, binds to the C-terminus of PTEN and regulates its turnover. Five Ser/Thr residues within the C-terminal segment of PTEN, including Ser-380, are phosphorylated upon binding of PTEN to PICT-1 and may contribute to the stabilization of PTEN. PICT-1 is localized to the nucleus and/or nucleolus and is highly expressed in pancreas and heart, but can also be detected in liver, skeletal muscle, placenta and kidney. PICT-1 also interacts with herpes simplex virus 1 regulatory proteins ICP22 and ICP0. The tumor suppressor GLTSCR2 gene, which encodes PICT-1, is located in a 150-kb minimal common deletion region for human gliomas, especially oligodendrogliomas, and maps to human chromosome 19q13.3.
- 基因ID
- 29997
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