AMHR2 抗体 (AA 21-120)
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- 抗原 See all AMHR2 抗体
- AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))
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抗原表位
- AA 21-120
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AMHR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MISRII/AMHR2
- 亚型
- IgG
- Top Product
- Discover our top product AMHR2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))
- 别名
- AMHR2 (AMHR2 产品)
- 别名
- AMHR antibody, MISR2 antibody, MISRII antibody, MRII antibody, Misiir antibody, Misrii antibody, Mrii antibody, anti-Mullerian hormone receptor type 2 antibody, anti-Mullerian hormone type 2 receptor antibody, AMHR2 antibody, Amhr2 antibody
- 背景
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Synonyms: AMH type II receptor, AMHR2, AMHR2_HUMAN, Anti-Muellerian hormone type II receptor, Anti-Muellerian hormone type-2 receptor, MGC141312, MIS type II receptor, MISRII, MRII, Muellerian hormone type 2 receptor, Muellerian hormone type II receptor, Mullerian hormone receptor type II.
Background: MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
- 基因ID
- 269
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