POLD1 抗体 (AA 101-200)
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北京 101111
Quick Overview for POLD1 抗体 (AA 101-200) (ABIN1714356)
抗原
See all POLD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DNA polymerase delta
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亚型
- IgG
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anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) antibody
POLD1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) (Center) antibodyPOLD1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) (AA 1-123), (Catalytic Subunit) antibodyPOLD1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) (AA 41-254) antibodyPOLD1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) antibodyKD Validated POLD1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3335 unconjugated Recombinant Antibody
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) antibodyPOLD1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) (C-Term) antibodyPOLD1 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) (AA 710-739) antibodyPOLD1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB17790 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))
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别名
- DNA polymerase delta
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背景
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Synonyms: DNA polymerase delta subunit 2; DNA polymerase delta subunit p50; DNA polymerase subunit delta 2; DNA polymerase subunit delta p50; DPOD2_HUMAN; POLD 2; POLD2.
Background: DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases (1). In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches (2). These exonucleases include the family of DNA polymerases (3). DNA pol , _, ∂, and e are involved in DNA replication and repair (4). DNA pol ∂ and DNA pol e are multisubunit enzymes, with DNA pol ∂ consisting of two subunits p125, which interacts with the sliding DNA clamp protein PCNA, and p50 (5). The nuclear-encoded DNA pol © is the only DNA polymerase required for the replication of the mitochondrial DNA (6). DNA pol is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis (7). DNA pol œ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks (8).
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基因ID
- 5425
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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