EPOR 抗体 (pTyr485)
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- 抗原 See all EPOR 抗体
- EPOR (Erythropoietin Receptor (EPOR))
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抗原表位
- pTyr485
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPOR antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human EPO Receptor around the phosphorylation site of Tyr485
- 亚型
- IgG
- Top Product
- Discover our top product EPOR Primary Antibody
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anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 301-450) antibodyEPOR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 470-504), (C-Term) antibodyEPOR 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB50846 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 45-244) antibodyEPOR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibodyEPOR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 274-508) antibodyEPOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 320-506) antibodyEPOR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR 适用: 人 FACS, cELISA 宿主: 小鼠 Monoclonal VP-2E8 unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- EPOR (Erythropoietin Receptor (EPOR))
- 别名
- EPO Receptor (EPOR 产品)
- 别名
- EPOR antibody, epor antibody, EPO-R antibody, erythropoietin receptor antibody, erythropoietin receptor L homeolog antibody, EPOR antibody, epor antibody, Epor antibody, epor.L antibody
- 背景
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Synonyms: EPO Receptor phospho Y485, p-EPO Receptor phospho Y485, EPOR phospho Y485, p-EPOR phospho Y485, erythropoietin receptor, EPO R, EPO Receptor, Erythropoietin receptor precursor.
Background: The erythropoietin receptor (EPOR) is a member of the cytokine receptor family. There are several isoforms including: EPOR-F (full length), EPOR-S (soluble form), and EPOR-T (truncated form). Upon erythropoietin (EPO) binding, the EPOR activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated EPOR appears to have a role in erythroid cell survival. Defects in the EPOR may produce erythroleukemia and familial erythrocytosis. A functional EPOR is found in the cardiovascular system, including endothelial cells and cardiomyocytes, and data suggest that the EPO/EPO receptor system plays an important role in cardiac function. In animal studies, treatment with EPO during ischemia/reperfusion in the heart has been shown to limit the infarct size and the extent of apoptosis.
- 基因ID
- 2057
- 途径
- JAK/STAT Signaling
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