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ATM 抗体 (pSer794)

This anti-ATM antibody is a 兔 多克隆 antibody detecting ATM in ELISA, IHC (p), IF (p), ICC, IF (cc) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1713603
发货至: 中国

Quick Overview for ATM 抗体 (pSer794) (ABIN1713603)

抗原

See all ATM 抗体
ATM (Ataxia Telangiectasia Mutated (ATM))

适用

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宿主

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克隆类型

  • 123
  • 40
多克隆

标记

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This ATM antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    • 2
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    • 1
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    • 1
    • 1
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    pSer794

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human ATM around the phosphorylation site of Ser794

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ATM (Ataxia Telangiectasia Mutated (ATM))

    别名

    ATM

    背景

    Synonyms: ATM Ser794, ATM phospho S794, p-ATM Ser794, p-ATM S794, AT complementation group A, AT complementation group C, AT complementation group D, AT complementation group E, AT mutated, AT protein,AT1,ATA,Ataxia telangiectasia gene mutated in human beings, Ataxia telangiectasia mutated, ATC, ATDC, ATE, ATM, Human phosphatidylinositol 3 kinase homolog, Serine protein kinase ATM, T cell prolymphocytic leukemia, TEL1, TPLL, ATM_HUMAN.

    Background: ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).

    基因ID

    472

    途径

    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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