Girdin 抗体 (pTyr1765)
Quick Overview for Girdin 抗体 (pTyr1765) (ABIN1713601)
抗原
See all Girdin (CCDC88A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1765
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human APE around the phosphorylation site of Tyr1765
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1401-1500) antibody
CCDC88A 适用: 人 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pSer417) antibodyCCDC88A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1571-1870) antibodyCCDC88A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
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别名
- Girdin
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背景
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Synonyms: Girdin phospho Y1765, p-Girdin phospho Y1765, Akt phosphorylation enhancer, APE, Coiled coil domain containing protein 88A, G alpha interacting vesicle associated protein, Girders of actin filament, GIV, HkRP1, Hook related protein 1, AKT iphosphorylation enhancer, Akt phosphorylation enhancer, Ccdc88a, GIV, GRDN, GRDN_HUMAN, HkRP1, Hook related protein 1, Hook-related protein 1, KIAA1212.
Background: Girdin is a 1,871 amino acid protein that, via interactions with phosphoinositides, localizes to the cell membrane and to the cytosol. Expressed ubiquitously, girdin functions to enhance the activity of PI 3-kinase-dependent phosphorylation of proteins, such as Akt1, thereby inducing the phosphorylation of downstream protein targets and, ultimately, regulating DNA replication and cellular proliferation. Additionally, girdin is crucial for cell migration and is responsible for both maintaining the structural integrity of the Actin cytoskeleton and for regulating the formation of Actin stress fibers. Girdin exists as a homodimer that can itself be phosphorylatedan event that delocalizes girdin from the cell membrane, thus allowing it to participate in cell migration events. Two isoforms of girdin exist due to alternative splicing events.
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基因ID
- 55704
抗原
-
