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POLH 抗体 (AA 51-160) (Cy3)

This anti-POLH antibody is a 兔 多克隆 antibody detecting POLH in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1702075
发货至: 中国

Quick Overview for POLH 抗体 (AA 51-160) (Cy3) (ABIN1702075)

抗原

See all POLH 抗体
POLH (Polymerase (DNA Directed), eta (POLH))

适用

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宿主

  • 43
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克隆类型

  • 45
  • 1
多克隆

标记

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This POLH antibody is conjugated to Cy3

应用范围

  • 33
  • 13
  • 12
  • 12
  • 9
  • 5
  • 5
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  • 2
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 51-160

    预测反应

    Human,Mouse,Rat,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DNA polymerase eta

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    POLH (Polymerase (DNA Directed), eta (POLH))

    别名

    DNA polymerase eta

    背景

    Synonyms: DNA polymerase eta, FLJ16395, FLJ21978, POLH, POLH_HUMAN, polymerase DNA directed eta, RAD30, RAD30 homolog A, RAD30A, Xeroderma pigmentosum variant type protein, XP V, XPV.

    Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.

    基因ID

    5429

    途径

    DNA Damage Repair
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