UCMA 抗体 (AA 21-120) (Biotin)
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- 抗原 See all UCMA 抗体
- UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))
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抗原表位
- AA 21-120
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UCMA antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human UCMA
- 亚型
- IgG
- Top Product
- Discover our top product UCMA Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))
- 别名
- UCMA (UCMA 产品)
- 别名
- BN antibody, GRP-10 antibody, preproGRP antibody, proGRP antibody, grp antibody, GRP2 antibody, ucma antibody, zgc:162317 antibody, C10orf49 antibody, GRP antibody, RGD1308977 antibody, 1110017I16Rik antibody, AW121955 antibody, Grp antibody, GRP1 antibody, zgc:85838 antibody, gastrin releasing peptide antibody, upper zone of growth plate and cartilage matrix associated antibody, upper zone of growth plate and cartilage matrix associated L homeolog antibody, upper zone of growth plate and cartilage matrix associated a antibody, upper zone of growth plate and cartilage matrix associated b antibody, GRP antibody, UCMA antibody, ucma.L antibody, ucmaa antibody, ucma antibody, Ucma antibody, ucmab antibody
- 背景
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Synonyms: C10orf49, Gla rich protein, Gla-rich protein, Grp, GRP, OTTMUSP00000011599, RP23-272I15.1, UCMA, Ucma-C, UCMA_HUMAN, Unique cartilage matrix associated protein, Unique cartilage matrix-associated protein C-terminal fragment, Upper zone of growth plate and cartilage matrix associated.
Background: UCMA is a 138 amino acid secreted protein that is highly expressed in resting chrondrocytes in developing long bones and is thought to function in the early phase of chrondrocyte differentiation. A furin-like protease processes UCMA into an N-terminal 37 amino acid peptide and a C-terminal 74 amino acid peptide, which is referred to as Unique cartilage matrix-associated protein C-terminal fragment (Ucma-C). Introduction of recombinant Ucma-C interferes with osteogenic differentiation of mesenchymal stem cells, MC3T3-E1 preosteoblasts and primary osteoblasts. This suggests that Ucma may be involved in the negative regulation of osteogenic differentiation of osteochondrogenic precursor cells at the cartilage-bone interface and in peripheral zones of fetal cartilage.
- 基因ID
- 221044
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