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PRELP 抗体 (AA 151-250) (Biotin)

PRELP 适用: 人 IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1700383
发货至: 中国
  • 抗原 See all PRELP 抗体
    PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    适用
    • 28
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 24
    • 3
    • 1
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    This PRELP antibody is conjugated to Biotin
    应用范围
    • 25
    • 15
    • 15
    • 7
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Cow,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PRELP
    亚型
    IgG
    Top Product
    Discover our top product PRELP Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
    别名
    PRELP (PRELP 产品)
    别名
    7330409J17Rik antibody, SLRR2A antibody, MST161 antibody, MSTP161 antibody, proline arginine-rich end leucine-rich repeat antibody, proline and arginine rich end leucine rich repeat protein antibody, Prelp antibody, PRELP antibody
    背景

    Synonyms: 55 kDa leucine rich repeat protein of articular cartilage, MST161, MSTP161, Prelp, PRELP_HUMAN, Prolargin, Prolargin proteoglycan, Proline arginine rich end leucine rich repeat protein, Proline-arginine-rich end leucine-rich repeat protein, Proline/arginine rich end leucine rich repeat protein, SLRR2A.

    Background: PRELP (proline/arginine-rich end leucine-rich repeat protein), also known as Prolargin, MST161, SLRR2A or MSTP161, is a 382 amino acid secreted protein that localizes to the extracellular matrix. Belonging to the Class II subfamily of the small leucine-rich proteoglycan (SLRP) family, PRELP contains twelve LRR (leucine-rich) repeats, which are motifs consisting of 20-29 residues that are present in numerous proteins with diverse functions and provide versatile structural framework for the formation of protein-protein interactions. Highly expressed in cartilage, basement membranes and developing bone, PRELP is considered a glycosaminoglycan (GAG)- and collagen-binding anchor protein that associates with the basement membrane heparan sulfate proteoglycan perlecan. PRELP acts as a linker between the extracellular matrix and the cell surface of proteoglycans and may be partially responsible for Hutchinson-Gilford progeria (HGP), an extremely rare genetic disorder that causes premature, rapid aging shortly after birth.

    途径
    Glycosaminoglycan Metabolic Process
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