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GPR17 抗体 (AA 2-100) (Alexa Fluor 555)

GPR17 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN1696669
发货至: 中国
  • 抗原 See all GPR17 抗体
    GPR17 (G Protein-Coupled Receptor 17 (GPR17))
    抗原表位
    • 14
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-100
    适用
    • 59
    • 14
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 59
    • 1
    克隆类型
    • 60
    多克隆
    标记
    • 23
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPR17 antibody is conjugated to Alexa Fluor 555
    应用范围
    • 38
    • 31
    • 18
    • 13
    • 13
    • 13
    • 10
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human G protein coupled receptor 17
    亚型
    IgG
    Top Product
    Discover our top product GPR17 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GPR17 (G Protein-Coupled Receptor 17 (GPR17))
    别名
    GPR17 (GPR17 产品)
    别名
    GPR17 antibody, AI853548 antibody, G protein-coupled receptor 17 antibody, GPR17 antibody, Gpr17 antibody
    背景

    Synonyms: DKFZp686M18273, G protein coupled receptor 17, G-protein coupled receptor 17, GPR 17, Gpr17, GPR17_HUMAN, P2Y like receptor, P2Y-like receptor, Probable P2Y purinoceptor GPR 17, Probable P2Y purinoceptor GPR17, R12, UDP/CysLT receptor, Uracil nucleotide/cysteinyl leukotriene receptor, GPCR GPR17.

    Background: G protein-coupled receptor 17, GPR17, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins. While GPR17 is expressed in kidney, heart and umbilical vein endothelial cells, it is expressed in the highest levels in the brain. Upon brain injury, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, increase significantly at the site of damage. In some neurons, GPR17, a membrane receptor for uracil nucleotide and CysLTs, is upregulated as well, infiltrating the lesioned area. GPR17 is thought to play a role in mediating neuronal death, remodeling brain circuitries by microglia and initiating remyelination in damaged neurons. Two named isoforms of GPR17 exist as a result of alternative splicing events.

    基因ID
    2840
    UniProt
    Q13304
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