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SCIMP 抗体 (AA 1-100) (Alexa Fluor 488)

SCIMP 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN1694757
发货至: 中国
  • 抗原 See all SCIMP 抗体
    SCIMP (SLP Adaptor and CSK Interacting Membrane Protein (SCIMP))
    抗原表位
    • 14
    • 4
    AA 1-100
    适用
    宿主
    • 19
    • 4
    克隆类型
    • 19
    • 4
    多克隆
    标记
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCIMP antibody is conjugated to Alexa Fluor 488
    应用范围
    • 12
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human C17orf87
    亚型
    IgG
    Top Product
    Discover our top product SCIMP Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SCIMP (SLP Adaptor and CSK Interacting Membrane Protein (SCIMP))
    别名
    C17orf87 (SCIMP 产品)
    别名
    C17orf87 antibody, UNQ5783 antibody, A430084P05Rik antibody, SLP adaptor and CSK interacting membrane protein antibody, SCIMP antibody, Scimp antibody
    背景

    Synonyms: C17orf87, CQ087_HUMAN, DTFT5783, SCIMP, SLP adaptor and CSK interacting membrane protein, SLP65/SLP76, Transmembrane protein C17orf87, UNQ5783, UNQ5783/PRO16090.

    Background: C17orf87 (chromosome 17 open reading frame 87) is a 145 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

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