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UQCRC1 抗体 (AA 156-480)

UQCRC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1683221
发货至: 中国
  • 抗原 See all UQCRC1 抗体
    UQCRC1 (Ubiquinol-Cytochrome C Reductase Core Protein I (UQCRC1))
    抗原表位
    • 14
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 156-480
    适用
    • 47
    • 10
    • 9
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 39
    • 8
    克隆类型
    • 41
    • 6
    多克隆
    标记
    • 30
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UQCRC1 antibody is un-conjugated
    应用范围
    • 39
    • 19
    • 11
    • 9
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LEDSQIEKER DVILREMQEN DASMRDVVFN YLHATAFQGT PLAQAVEGPS ENVRKLSRAD LTEYLSTHYK APRMVLAAAG GVEHQQLLDL AQKHLGGIPW TYAEDAVPTL TPCRFTGSEI RHRDDALPFA HVAIAVEGPG WASPDNVALQ VANAIIGHYD CTYGGGVHLS SPLASGAVAN KLCQSFQTFS ICYAETGLLG AHFVCDRMKI DDMMFVLQGQ WMRLCTSATE SEVARGKNIL RNALVSHLDG TTPVCEDIGR SLLTYGRRIP LAEWESRIAE VDASVVREIC SKYIYDQCPA VAGYGPIEQL PDYNRIRSGM FWLRF
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 156-480 of human UQCRC1 (NP_003356.2).
    亚型
    IgG
    Top Product
    Discover our top product UQCRC1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    UQCRC1 (Ubiquinol-Cytochrome C Reductase Core Protein I (UQCRC1))
    别名
    UQCRC1 (UQCRC1 产品)
    别名
    MGC53748 antibody, zgc:73404 antibody, zgc:85750 antibody, 1110032G10Rik antibody, D3S3191 antibody, QCR1 antibody, UQCR1 antibody, ubiquinol-cytochrome c reductase core protein 1 L homeolog antibody, ubiquinol-cytochrome c reductase core protein 1 antibody, ubiquinol-cytochrome c reductase core protein I antibody, cytochrome b-c1 complex subunit 1, mitochondrial antibody, uqcrc1.L antibody, uqcrc1 antibody, UQCRC1 antibody, LOC100020379 antibody, LOC100074417 antibody, LOC100347571 antibody, LOC100413740 antibody, LOC100452425 antibody, Uqcrc1 antibody
    背景
    Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (By similarity. The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties (By similarity. May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS/subunit 9 when incorporated into complex III (Probable.,UQCRC1,D3S3191,QCR1,UQCR1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,UQCRC1
    分子量
    52 kDa
    基因ID
    7384
    UniProt
    P31930
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