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PIDD 抗体 (AA 1-85)

This anti-PIDD antibody is a 兔 多克隆 antibody detecting PIDD in IHC, WB 和 IF. Suitable for 人.
产品编号 ABIN1680710
发货至: 中国

Quick Overview for PIDD 抗体 (AA 1-85) (ABIN1680710)

抗原

See all PIDD 抗体
PIDD (P53-Induced Death Domain Protein (PIDD))

适用

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宿主

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克隆类型

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多克隆

标记

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This PIDD antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-85

    序列

    MAATVEGPEL EAAAAAGDAS EDSDAGSRAL PFLGGNRLSL DLYPGGCQQL LHLCVQQPLQ LLQVEFLRLS THEDPQLLEA TLAQL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP_665893.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:100

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PIDD (P53-Induced Death Domain Protein (PIDD))

    别名

    PIDD

    背景

    The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.,PIDD1,LRDD,PIDD,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,PIDD

    分子量

    33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa

    基因ID

    55367

    UniProt

    Q9HB75

    途径

    p53 Pathway, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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