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PIDD 抗体 (Middle Region)

PIDD 适用: 人, 大鼠, 小鼠, 豚鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787144
发货至: 中国
  • 抗原 See all PIDD 抗体
    PIDD (P53-Induced Death Domain Protein (PIDD))
    抗原表位
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 大鼠, 小鼠, 豚鼠, Cow, 犬
    宿主
    • 33
    • 3
    克隆类型
    • 33
    • 3
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIDD antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    RRDPEQVLLQ CLPRNKVDAT LRRLLERYRG PEPSDTVEMF EGEEFFAAFE
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 86%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against LRDD. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human LRDD
    Top Product
    Discover our top product PIDD Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 753 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PIDD (P53-Induced Death Domain Protein (PIDD))
    别名
    LRDD (PIDD 产品)
    别名
    1200011D09Rik antibody, AU042446 antibody, Pidd antibody, LRDD antibody, Lrdd antibody, p53 induced death domain protein 1 antibody, p53-induced death domain protein 1 antibody, Pidd1 antibody, PIDD1 antibody
    背景
    The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: DKFZp434D229, MGC16925, PIDD, LRDD
    Protein Interaction Partner: CRADD, CRYAB, MDFI, SOX8, KEAP1, TEAD3, MAFG, AFP, RPAP3, FANCI, SENP3, TRIM32, ANP32B, HAX1, TELO2, NUP93, AIFM1, RFC5, RFC4, PRKDC, PPP6C, POLR2B, POLD1, PCNA, PRDX1, MCM7, ERCC5, ERCC2, DDB1, CASP2, FADD, RIPK1, IKBKG, CCDC85B, EFEMP2, MADD,
    Protein Size: 753
    分子量
    83 kDa
    基因ID
    55367
    NCBI登录号
    NM_018494, NP_060964
    途径
    p53 Pathway, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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