(3 references)-
- 抗原 See all PIDD 抗体
- PIDD (P53-Induced Death Domain Protein (PIDD))
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抗原表位
- AA 776-910
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIDD antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)
- 特异性
- Recognizes human and the native form of mouse PIDD. Detects bands of ~90 kDa (full length protein) and ~50 kDa (cleaved protein) by Western blot.
- 交叉反应
- 人, 小鼠
- 免疫原
- Recombinant human PIDD (Death Domain: aa 776-910).
- Top Product
- Discover our top product PIDD Primary Antibody
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anti-P53-Induced Death Domain Protein (PIDD) (AA 1-85) antibody
PIDD 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) antibodyPIDD 适用: 人, 大鼠, 小鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 776-910) antibodyPIDD 适用: 人 IHC, WB, ELISA, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 3C5G8 unconjugated
anti-P53-Induced Death Domain Protein (PIDD) antibodyPIDD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 776-910) antibodyPIDD 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal Anto-1 unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 467-516) antibodyPIDD 适用: 人, 豚鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 143-192) antibodyPIDD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 668-917) antibodyPIDD 适用: 大鼠 IHC, WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (Middle Region) antibodyPIDD 适用: 人, 大鼠, 小鼠, 豚鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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: "Heat shock induces apoptosis independently of any known initiator caspase-activating complex." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 16991-7000, (2006) (PubMed).
: "PIDD mediates NF-kappaB activation in response to DNA damage." in: Cell, Vol. 123, Issue 6, pp. 1079-92, (2005) (PubMed).
: "The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress." in: Science (New York, N.Y.), Vol. 304, Issue 5672, pp. 843-6, (2004) (PubMed).
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: "Heat shock induces apoptosis independently of any known initiator caspase-activating complex." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 16991-7000, (2006) (PubMed).
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- 抗原
- PIDD (P53-Induced Death Domain Protein (PIDD))
- 别名
- PIDD (PIDD 产品)
- 别名
- 1200011D09Rik antibody, AU042446 antibody, Pidd antibody, LRDD antibody, Lrdd antibody, p53 induced death domain protein 1 antibody, p53-induced death domain protein 1 antibody, Pidd1 antibody, PIDD1 antibody
- 背景
- PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
- UniProt
- Q9HB75
- 途径
- p53 Pathway, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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