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CD8B 抗体 (FITC)

CD8B 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 3-4-1 FITC
产品编号 ABIN161260
发货至: 中国
  • 抗原 See all CD8B 抗体
    CD8B (CD8b Molecule (CD8B))
    适用
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    大鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD8B antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Rat CD8b
    免疫原
    Rat/mouse T cell hybrids expressing CD8 . Fusion Partner: X63 Ag.653 myeloma cell line . Donor: BALB/c mouse spleen cells
    克隆位点
    3-4-1
    亚型
    IgG1
    Top Product
    Discover our top product CD8B Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    0.1 mg/ml
    缓冲液
    FITC conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography).
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    CD8B (CD8b Molecule (CD8B))
    别名
    CD8b (CD8B 产品)
    别名
    Cd8b antibody, Ly-3 antibody, Ly-C antibody, Lyt-3 antibody, CD8B1 antibody, LEU2 antibody, LY3 antibody, LYT3 antibody, P37 antibody, Cd8b1 antibody, CD8b molecule antibody, CD8 antigen, beta chain 1 antibody, Cd8b antibody, CD8B antibody, Cd8b1 antibody
    背景
    Anti-rat CD8b monoclonal antibody reacts with the beta chain of the CD8 differentiation antigen. CD8b is expressed on most thymocytes and mature T cytotoxic/ suppressor cells (MHC class I restricted). While the CD8a and CD8b form a heterodimer on the surface of thymocytes and thymus-dependent T cytotoxic/suppressor cells, the majority of NK cells, many CD8 T cells from athymic rats, many activated CD4 T cells, and intestinal epithelium lymphocytes (IEL) express CD8a without CD8b. This suggests that expression of the CD8 heterodimer (a/b) is more dependant on intrathymic T cell maturation than that of the homodimer (a/a). The thymus dependence of CD8a/b T cells may be due to a requirement for thymic selection on self MHC class I antigens. Reported applications for this antibody include flow cytometry, immunoprecipitation and Western blotting. The 3.4.1 antibody also blocks both activation in an allogenic response and cell mediated cytotoxicity by CD8 T cells.
    途径
    TCR Signaling
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