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VEGFA 抗体

VEGFA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1589726
发货至: 中国
  • 抗原 See all VEGFA 抗体
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
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    多克隆
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    This VEGFA antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    Recombinant human VEGF165 RT #300-036)
    产品特性
    Chromosomal location: 6p12
    Produced from sera of rabbits immunized with highly pure recombinant human VEGF165.
    纯化方法
    Anti-human VEGF-A was purified by affinity chromatography with immobilized Protein A.
    亚型
    IgG
    Top Product
    Discover our top product VEGFA Primary Antibody
  • 应用备注
    IP: use 1-5 µg/mL
    说明

    Rabbit IG Polyclonal Antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS
    注意事项
    Centrifuge vial prior to opening.
    储存条件
    -20 °C
    储存方法
    The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C
    有效期
    6 months
  • 抗原
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    别名
    VEGF-A (VEGFA 产品)
    别名
    MVCD1 antibody, VEGF antibody, VPF antibody, Vegf antibody, Vegf120 antibody, Vegf164 antibody, Vegf188 antibody, Vpf antibody, vegf antibody, vegfa antibody, wu:fj82c06 antibody, VEGF-A antibody, VEGF164 antibody, eVEGF120 antibody, eVEGF164 antibody, vegf-a antibody, vpf antibody, vefg antibody, si:dkey-14d8.3 antibody, wu:fd42e02 antibody, vascular endothelial growth factor A antibody, vascular endothelial growth factor Aa antibody, vascular endothelial growth factor A L homeolog antibody, vascular endothelial growth factor Ab antibody, VEGFA antibody, Vegfa antibody, vegfaa antibody, vegfa.L antibody, vegfa antibody, vegfab antibody
    背景
    Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF) or vasculotropin, is a homodimeric 34 - 42 kDa, heparin-binding glycoprotein with potent angiogenic, mitogenic and vascular permeability-enhancing activities specific for endothelial cells. Different isoforms can be generated by differential splicing (e.g. VEGF165). All eight cysteine residues involved in intra- and inter-chain disulfide bonds are conserved among these growth factors. A cDNA encoding a protein having a 53% amino acid sequence homology in the PDGF-like region of VEGF has been isolated from a human placental cDNA library. This protein, named placenta growth factor (PlGF), is now recognized to be a member of the VEGF family of growth factors. Two receptor tyrosine kinases have been described as putative VEGF receptors. Flt-1 (fms-like tyrosine kinase), and KDR (kinase-insert-domain-containing receptor) proteins have been shown to bind VEGF-A with high affinity. In vitro, VEGF is a potent endothelial cell mitogen. The antibody is against the N-terminus and will recognize all VEGF-A isoforms.
    Synonyms: VEGFA, VPF, VEGF, MVCD1
    NCBI登录号
    NM_001171626, NP_001165097
    UniProt
    P15692
    途径
    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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