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VEGFA 抗体 (AA 207-371)

VEGFA 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 6G5A10 unconjugated
产品编号 ABIN5542402
发货至: 中国
  • 抗原 See all VEGFA 抗体
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    抗原表位
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    AA 207-371
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This VEGFA antibody is un-conjugated
    应用范围
    • 205
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human VEGFA (AA: 207-371) expressed in E. coli.
    克隆位点
    6G5A10
    亚型
    IgG1
    Top Product
    Discover our top product VEGFA Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    别名
    VEGFA (VEGFA 产品)
    别名
    MVCD1 antibody, VEGF antibody, VPF antibody, Vegf antibody, Vegf120 antibody, Vegf164 antibody, Vegf188 antibody, Vpf antibody, vegf antibody, vegfa antibody, wu:fj82c06 antibody, VEGF-A antibody, VEGF164 antibody, eVEGF120 antibody, eVEGF164 antibody, vegf-a antibody, vpf antibody, vefg antibody, si:dkey-14d8.3 antibody, wu:fd42e02 antibody, vascular endothelial growth factor A antibody, vascular endothelial growth factor Aa antibody, vascular endothelial growth factor A L homeolog antibody, vascular endothelial growth factor Ab antibody, VEGFA antibody, Vegfa antibody, vegfaa antibody, vegfa.L antibody, vegfa antibody, vegfab antibody
    背景

    Description: This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.,

    Aliases: VPF, VEGF, MVCD1

    分子量
    27 kDa
    基因ID
    7422
    HGNC
    7422
    途径
    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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