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- 抗原
- p39
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 特异性
- P39 Antibody, pAb, Rabbit detects endogenous levels of human, mouse, and rat p39.Positive Control: HEK293, SH-SY5Y, mouse and rat brain
- 交叉反应 （详细）
- p39 Antibody, pAb, Rabbit detects endogenous levels of human, mouse, and rat p39.Positive Control: HEK293, SH-SY5Y, mouse and rat brain
- 纯化方法
- Immunoaffinity chromatography
- 免疫原
- KLH-coupled synthetic peptide from C-terminal of human p39
- 亚型
- IgG
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anti-p39 antibody
适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-p39 antibody适用: Borrelia burgdorferi, Borrelia afzelii WB, LF 宿主: 兔 Polyclonal unconjugated
anti-p39 (Center) antibody适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-p39 (Internal Region) antibody适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 2-4 µg/mLOther Applications: User optimized - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4, containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
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- 抗原
- p39
- 别名
- AP-1 antibody, AP1 antibody, c-Jun antibody, B230310J22Rik antibody, p39 antibody, Jun proto-oncogene, AP-1 transcription factor subunit antibody, cyclin-dependent kinase 5, regulatory subunit 2 (p39) antibody, JUN antibody, Jun antibody, Cdk5r2 antibody
- 背景
- P35 and p39 are neuronal-specific regulatory subunit of Cyclin-dependent kinase 5 (CDK5). Both p35 and p39 are expressed in the brain and have been implicated in the regulation of the neuronalcytoskeleton and synaptic function via the control of CDK5 activity. N-terminal of p35 and p39 associates with alpha-actinin-1 while CaMKII could bind to the C-terminus of p35 and p39. Association of p39 with CDK5 promotes Munc18-1 phosphorylation and Ca2+-dependent exocytosis. Phosphorylation of p39 by CDK5 plays a role in the regulation of p39/cdk5 kinase.p39 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human p39 (Swiss Prot: Q13319).
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