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- 抗原 See all EEA1 抗体
- EEA1 (Early Endosome Antigen 1 (EEA1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EEA1 antibody is un-conjugated
- 应用范围
- 请咨询
- 特异性
- Rabbit Anti-EEA1 Polyclonal Antibody detects endogenous levels of human, mouse and rat EEA1 protein.
- 交叉反应
- 小鼠, 大鼠
- 产品特性
- Rabbit Anti-EEA1 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human EEA1 (Swiss Prot: Q15075).
- 纯化方法
- Immunoaffinity chromatography
- 免疫原
- KLH-coupled synthetic peptide from N-terminal of human EEA1
- 亚型
- IgG
- Top Product
- Discover our top product EEA1 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
- 浓度
- 0.5 mg/mL
- 缓冲液
- Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
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Dynamics of exosome internalization and trafficking." in: Journal of cellular physiology, Vol. 228, Issue 7, pp. 1487-95, (2013) (PubMed).
: "Phosphoinositide 3-kinase? controls the intracellular localization of CpG to limit DNA-PKcs-dependent IL-10 production in macrophages." in: PLoS ONE, Vol. 6, Issue 10, pp. e26836, (2011) (PubMed).
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Dynamics of exosome internalization and trafficking." in: Journal of cellular physiology, Vol. 228, Issue 7, pp. 1487-95, (2013) (PubMed).
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- 抗原
- EEA1 (Early Endosome Antigen 1 (EEA1))
- 别名
- EEA1 (EEA1 产品)
- 别名
- MST105 antibody, MSTP105 antibody, ZFYVE2 antibody, im:7151048 antibody, si:ch211-276p10.2 antibody, A430109M19Rik antibody, B230358H09Rik antibody, early endosome antigen 1 antibody, early endosome antigen 1 S homeolog antibody, EEA1 antibody, eea1 antibody, Eea1 antibody, eea1.S antibody
- 背景
- Early endosomal antigen 1 (EEA1) is an early endosomal marker which is essential for fusion between early endocytic vesicles. It interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion. EEA1 protein contains an N-terminal zinc finger motif and a cys-rich C-terminal metal-binding finger. A FYVE domain located at the carboxy terminus of EEA1 binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes.
- 分子量
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Predicted Band Size: 162 KD
Observed Band Size: 162 KD - UniProt
- Q15075
- 途径
- Toll-Like Receptors Cascades
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