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WDR77 抗体 (C-Term)

WDR77 适用: 人, Orang-Utan ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1574092
发货至: 中国
  • 抗原 See all WDR77 抗体
    WDR77 (WD Repeat Domain 77 (WDR77))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    C-Term
    适用
    • 37
    • 16
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    人, Orang-Utan
    宿主
    • 26
    • 11
    克隆类型
    • 26
    • 11
    多克隆
    标记
    • 26
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WDR77 antibody is un-conjugated
    应用范围
    • 21
    • 13
    • 8
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    特异性
    Rabbit Anti-MEP50 Polyclonal Antibody detects endogenous levels of human MEP50 protein. It is predicted to react with sumatran orangutan MEP50 protein according to sequence homology.
    交叉反应 (详细)
    Rabbit Anti-MEP50 Polyclonal Antibody detects endogenous levels of human MEP50 protein. It is predicted to react with sumatran orangutan MEP50 protein according to sequence homology.
    纯化方法
    Immunoaffinity chromatography
    免疫原
    KLH-coupled synthetic peptide from carboxyl terminal of human MEP50
    亚型
    IgG
    Top Product
    Discover our top product WDR77 Primary Antibody
  • 应用备注
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

    ELISA: 0.05-0.2 µg/mL
    Western blot: 1-2 µg/mLOther Applications: user-optimized
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4, containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C/-20 °C
    储存方法
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
  • 抗原
    WDR77 (WD Repeat Domain 77 (WDR77))
    别名
    MEP50 (WDR77 产品)
    别名
    MEP-50 antibody, MEP50 antibody, Nbla10071 antibody, RP11-552M11.3 antibody, p44 antibody, p44/Mep50 antibody, 2610003I18Rik antibody, 2610312E17Rik antibody, C79984 antibody, p44/MEP50 antibody, RGD1310479 antibody, mep50 antibody, valois antibody, WDR77 antibody, zgc:65780 antibody, zgc:77274 antibody, WD repeat domain 77 antibody, WD repeat domain 77 S homeolog antibody, WDR77 antibody, Wdr77 antibody, wdr77.S antibody, wdr77 antibody
    背景
    MEP50 (methylosome protein 50), also known as WDR77, is a component of protein arginine methyltransferase complex containing at least PRMT5, CLNS1A and MEP50. It binds histone H2A selectively among core histones, and mediates transcriptional repression of protein arginine methyltransferase PRMT5. MEP50 is a WD repeat protein which interacts with an arginine protein JBP1. MEP50 plays a critical role in methylosome activity and may regulate the transfer of Sm proteins to the SMN (survival of motor neurons) complex, an early step in the assembly of U snRNPs. In addition, MEP50 may function to mediate the interaction of multiple substrates in the methylosome.Rabbit Anti-MEP50 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from carboxyl terminal of human MEP50. (Swiss Prot: Q9BQA1).
    途径
    Ribonucleoprotein Complex Subunit Organization
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