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RAB5 抗体 (AA 150-200)

RAB5A 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1574080
发货至: 中国
  • 抗原 See all RAB5 (RAB5A) 抗体
    RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
    抗原表位
    • 17
    • 15
    • 14
    • 7
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    • 1
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    • 1
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    • 1
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    AA 150-200
    适用
    • 94
    • 63
    • 43
    • 12
    • 11
    • 11
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    • 3
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    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 98
    • 8
    • 4
    • 2
    克隆类型
    • 95
    • 17
    多克隆
    标记
    • 49
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
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    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This RAB5 antibody is un-conjugated
    应用范围
    • 82
    • 40
    • 34
    • 30
    • 25
    • 18
    • 14
    • 13
    • 13
    • 7
    • 4
    • 4
    • 2
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    • 1
    Western Blotting (WB), ELISA
    特异性
    Rabbit Anti-Rab5 Polyclonal Antibody detects endogenous levels of human, mouse and rat Rab5 protein.
    纯化方法
    Immunoaffinity chromatography
    免疫原
    KLH-coupled synthetic peptide from within AA 150-200 of human Rab5 protein .
    亚型
    IgG
    Top Product
    Discover our top product RAB5A Primary Antibody
  • 应用备注
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

    ELISA: 0.05-0.2 µg/mL
    Western blot: 0.5-1 µg/mL
    Other applications: user-optimized
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4, containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C/-20 °C
    储存方法
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
  • 抗原
    RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
    别名
    Rab5 (RAB5A 产品)
    别名
    RAB5 antibody, 2410015H04Rik antibody, AI663973 antibody, AU021172 antibody, nnyRab5a antibody, DDBDRAFT_0168594 antibody, DDBDRAFT_0229401 antibody, DDB_0168594 antibody, DDB_0229401 antibody, rab5 antibody, RAB5A antibody, Rab5a antibody, rab5al antibody, zgc:56644 antibody, fj38g08 antibody, hm:zehn1144 antibody, rab5a antibody, wu:fj38g08 antibody, RAB5A, member RAS oncogene family antibody, rab5A protein antibody, Rab5a, GTPase antibody, predicted protein antibody, Rab GTPase antibody, RAB5A, member RAS oncogene family L homeolog antibody, RAB5A, member RAS oncogene family, b antibody, RAB5A, member RAS oncogene family, a antibody, RAB5A antibody, Rab5a antibody, rab5A antibody, rab5a antibody, rab5a.L antibody, rab5ab antibody, rab5aa antibody
    背景
    Small GTPase Rab5 is a member of Rab family which binds to GTP and exhibits GTPase activity. Rab5 protein is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway. Rabaptin-5 serves as an effector of Rab5 and mediates the tuberin association with Rab5. RNTRE protein whose activity is regulated by EGFR activates Rab5 GTPase. RNTRE acts on Rab5 and inhibits EGFR's internalization. The ALS2 protein specifically binds to Rab5 and functions as a guanine nucleotide exchange factor (GEF) for Rab5. As a key regulator of endocytosis, signal transduction, and mitogenesis, Rab5 protein is also a signaling GTPase that elucidates the major molecular elements of its downstream pathway.Rabbit Anti-Rab5 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from within residues 150-200 of human Rab5 protein (Swiss Prot: P20339).
    途径
    Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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