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ATP6V1B2 抗体

ATP6V1B2 适用: 人, 小鼠, 大鼠, Cow, 小鸡, Drosophila melanogaster WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1573989
发货至: 中国
  • 抗原 See all ATP6V1B2 抗体
    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
    适用
    • 28
    • 15
    • 15
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, Cow, 小鸡, Drosophila melanogaster
    宿主
    • 22
    • 6
    克隆类型
    • 24
    • 4
    多克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP6V1B2 antibody is un-conjugated
    应用范围
    • 20
    • 8
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    Rabbit Anti-V-ATPase Subunit B 2 Polyclonal Antibody reacts with human Anti-V-ATPase subunit B. Sequence homology predicts that it will also react with mouse, rat, chicken, bovine, and fruit fly V-ATPase subunit B 2.
    交叉反应 (详细)
    Rabbit Anti-V-ATPase Subunit B 2 Polyclonal Antibody reacts with human Anti-V-ATPase subunit B. Sequence homology predicts that it will also react with mouse, rat, chicken, bovine, and fruit fly V-ATPase subunit B 2.
    纯化方法
    Immunoaffinity chromatography
    亚型
    IgG
  • 应用备注
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

    ELISA: 0.03-0.125 µg/mL Western blot: 1.0 µg/mL Other applications: user-optimized
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, containing 30 % glycerol and 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid repeated freezing and thawing cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    The antibody is stable for 2-3 weeks if stored at 2-8 °C. For long term storage, aliquot and store at -28 °C or below.
  • Ahmad, Khundmiri, Pribble, Merchant, Ameen, Klein, Levi, Lederer: "Role of vacuolar ATPase in the trafficking of renal type IIa sodium-phosphate cotransporter." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 27, Issue 6, pp. 703-14, (2011) (PubMed).

  • 抗原
    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
    别名
    V-ATPase Subunit B 2 (ATP6V1B2 产品)
    别名
    Atp6b1b2 antibody, Atp6b2 antibody, Vatb antibody, vha55 antibody, VATB antibody, ATP6B1B2 antibody, ATP6B2 antibody, HO57 antibody, VPP3 antibody, Vma2 antibody, atp6v1bb antibody, fj51e01 antibody, vatB2 antibody, wu:fj51e01 antibody, zgc:109771 antibody, AI194269 antibody, AI790362 antibody, R74844 antibody, ATPase H+ transporting V1 subunit B2 antibody, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog antibody, ATPase, H+ transporting, lysosomal, V1 subunit B2 antibody, ATPase, H+ transporting, lysosomal V1 subunit B2 antibody, Atp6v1b2 antibody, atp6v1b2.S antibody, ATP6V1B2 antibody, atp6v1b2 antibody
    背景
    The V-ATPase subunit B 2 is related to a gene that encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.Rabbit Anti-V-ATPase Subunit B 2 Polyclonal Antibody is developed in rabbit using a synthetic peptide conjugated to KLH. It is purified from rabbit antiserum by immunoaffinity chromatography and supplied as 40 ug aliquot at concentration of 0.5 mg/ml.
    途径
    Transition Metal Ion Homeostasis, Proton Transport
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