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RYBP 抗体

RYBP 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN155069
发货至: 中国
  • 抗原 See all RYBP 抗体
    RYBP (RING1 and YY1 Binding Protein (RYBP))
    适用
    • 56
    • 33
    • 13
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 8
    克隆类型
    • 60
    • 6
    多克隆
    标记
    • 36
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RYBP antibody is un-conjugated
    应用范围
    • 57
    • 28
    • 13
    • 13
    • 10
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects DEDAF. A 32 kDa band should be detected.
    纯化方法
    Affinity purified
    免疫原
    Synthetic peptide surrounding amino acid 218 of human DEDAF.
    Top Product
    Discover our top product RYBP Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. A549 or HepG2 cell lysate can be used as a positive control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    RYBP (RING1 and YY1 Binding Protein (RYBP))
    别名
    RYBP (RYBP 产品)
    别名
    AAP1 antibody, DEDAF antibody, YEAF1 antibody, 2410018J24Rik antibody, rybp antibody, aap1 antibody, dedaf antibody, yeaf1 antibody, cb337 antibody, wu:fi34f03 antibody, Dedaf antibody, zgc:153842 antibody, RING1 and YY1 binding protein antibody, RING1 and YY1 binding protein L homeolog antibody, RING1 and YY1 binding protein a antibody, RING1 and YY1 binding protein b antibody, RYBP antibody, Rybp antibody, rybp antibody, rybp.L antibody, rybpa antibody, rybpb antibody
    背景
    Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10, and FADD was recently identified and designated DEDAF (for DED associated factor). DEDAF is identical to the transcriptional repressor RYBP. DEDAF interacts with FADD and augments the formation of CD95/FADD/caspase-8 complexes at the cytoplasm. DEDAF also interacts with DED-containing DNA biding protein (DEDD) in the nucleus, indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.Synonyms: AAP-1, APAP-1, Apoptin-associating protein 1, DED-associated factor, DEDAF, Death effector domain-associated factor, RING1 and YY1-binding protein, YEAF1, YY1 and E4TF1-associated factor 1
    基因ID
    23429
    NCBI登录号
    NP_036366
    UniProt
    Q8N488
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