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DDR2 抗体 (AA 290-320)

This anti-DDR2 antibody is a 小鼠 单克隆 antibody detecting DDR2 in WB. Suitable for 人.
产品编号 ABIN1539910
发货至: 中国

Quick Overview for DDR2 抗体 (AA 290-320) (ABIN1539910)

抗原

See all DDR2 抗体
DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

适用

  • 42
  • 24
  • 3
  • 1

宿主

  • 46
  • 7
小鼠

克隆类型

  • 43
  • 10
单克隆

标记

  • 34
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DDR2 antibody is un-conjugated

应用范围

  • 38
  • 31
  • 22
  • 6
  • 6
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

484CT5-5-4
  • 抗原表位

    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-320

    纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.

    亚型

    IgG1
  • 应用备注

    IHC: 1:200. WB: 1:100~1600

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    DDR2 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

    别名

    DDR2

    背景

    Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq].

    分子量

    96736

    基因ID

    4921

    NCBI登录号

    NP_001014796, NP_006173

    UniProt

    Q16832

    途径

    RTK signaling
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