Tuberin 抗体
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北京 101111
Quick Overview for Tuberin 抗体 (ABIN1539797)
抗原
See all Tuberin (TSC2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This TSC2 monoclonal antibody is generated from mouse immunized with TSC2 recombinant protein.
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亚型
- IgG1 kappa
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应用备注
- IF: 1:10~50. WB: 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- TSC2 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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别名
- TSC2
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背景
- Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 200608
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基因ID
- 7249
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NCBI登录号
- NP_000539, NP_001070651, NP_001107854
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UniProt
- P49815
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途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
抗原
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