SRRT 抗体 (N-Term)
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北京 101111
Quick Overview for SRRT 抗体 (N-Term) (ABIN1539452)
抗原
See all SRRT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 54-81, N-Term
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预测反应
- B, M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SRRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human SRRT.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- SRRT Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
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别名
- SRRT
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背景
- SRRT acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA), however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.
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分子量
- 100666
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基因ID
- 51593
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NCBI登录号
- NP_001122324, NP_001122325, NP_001122326, NP_056992
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UniProt
- Q9BXP5
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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