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TMPRSS12 抗体 (N-Term)

TMPRSS12 适用: 人 WB 宿主: 兔 Polyclonal RB35931 unconjugated
产品编号 ABIN2848477
发货至: 中国
  • 抗原 See all TMPRSS12 products
    TMPRSS12 (Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12))
    抗原表位
    • 8
    • 8
    • 7
    • 1
    • 1
    AA 26-54, N-Term
    适用
    • 17
    • 2
    • 2
    • 1
    • 1
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    This TMPRSS12 antibody is un-conjugated
    应用范围
    • 17
    • 12
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TMPRSS12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human TMPRSS12.
    克隆位点
    RB35931
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    TMPRSS12 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    TMPRSS12 (Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12))
    别名
    TMPRSS12 (TMPRSS12 产品)
    别名
    4930478A21Rik antibody, transmembrane protease, serine 12 antibody, transmembrane (C-terminal) protease, serine 12 antibody, TMPRSS12 antibody, tmprss12 antibody, Tmprss12 antibody
    背景
    TMPRSS12 (transmembrane protease serine 12) is a 348 amino acid single-pass membrane protein that belong to the peptidase S1 family and contains one peptidase S1 domain. The gene that encodes TMPRSS12 consists of nearly 45,000 bases and maps to human chromosome 12q13.12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism.
    分子量
    38605
    基因ID
    283471
    NCBI登录号
    NP_872365
    UniProt
    Q86WS5
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