This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TJP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 981-1009 amino acids from the C-terminal region of human TJP2.
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutation in this gene have been identified in patients with hypercholanemia. Alternate splicing results in multiple transcript variants.