This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This Mouse Tlk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of mouse Tlk1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Mouse Tlk1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
有效期
6 months
抗原
TLK1
(Tousled-Like Kinase 1 (TLK1))
别名
Tlk1
背景
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity). Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity).