This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This FOXP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-423 amino acids from the C-terminal region of human FOXP3.
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.