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LKB1 抗体 (C-Term)

This anti-LKB1 antibody is a 兔 多克隆 antibody detecting LKB1 in IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1537274
发货至: 中国

Quick Overview for LKB1 抗体 (C-Term) (ABIN1537274)

抗原

See all LKB1 (STK11) 抗体
LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

适用

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宿主

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克隆类型

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多克隆

标记

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This LKB1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB3549-3550
  • 抗原表位

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    AA 387-417, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-417 amino acids from the C-terminal region of human STK11 (LKB1).

    亚型

    Ig Fraction
  • 应用备注

    IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Dahmani, Just, Delay, Canal, Finzi, Prip-Buus, Lambert, Sujobert, Buchet-Poyau, Miller, Cavard, Marmier, Terris, Billaud, Perret: "A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties." in: Oncogene, Vol. 34, Issue 18, pp. 2337-46, (2015) (PubMed).

  • 抗原

    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

    别名

    STK11 (LKB1)

    背景

    STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

    分子量

    48636

    基因ID

    6794

    NCBI登录号

    NP_000446

    UniProt

    Q15831

    途径

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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