LKB1 抗体 (C-Term)
Quick Overview for LKB1 抗体 (C-Term) (ABIN1537274)
抗原
See all LKB1 (STK11) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 387-417, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-417 amino acids from the C-terminal region of human STK11 (LKB1).
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亚型
- Ig Fraction
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应用备注
- IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties." in: Oncogene, Vol. 34, Issue 18, pp. 2337-46, (2015) (PubMed).
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: "A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties." in: Oncogene, Vol. 34, Issue 18, pp. 2337-46, (2015) (PubMed).
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- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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别名
- STK11 (LKB1)
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背景
- STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
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分子量
- 48636
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基因ID
- 6794
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NCBI登录号
- NP_000446
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UniProt
- Q15831
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途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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