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- 抗原 See all ENC1 抗体
- ENC1 (Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1))
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抗原表位
- AA 395-423, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ENC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ENC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-423 amino acids from the C-terminal region of human ENC1.
- 克隆位点
- RB37065
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ENC1 Primary Antibody
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anti-Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1) (AA 17-98) antibody
ENC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1) (Internal Region) antibodyVerified ENC1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1) (AA 1-230) antibodyENC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1) (AA 17-98) antibodyENC1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1) (N-Term) antibodyENC1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1) (N-Term) antibodyENC1 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, Pig, 兔, 斑马鱼, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1) (AA 1-270) antibodyENC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- ENC1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- 有效期
- 6 months
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- 抗原
- ENC1 (Ectodermal-Neural Cortex 1 (With BTB-Like Domain) (ENC1))
- 别名
- ENC1 (ENC1 产品)
- 别名
- ENC1 antibody, LOC559101 antibody, CCL28 antibody, ENC-1 antibody, KLHL35 antibody, KLHL37 antibody, NRPB antibody, PIG10 antibody, TP53I10 antibody, Xencr-3 antibody, enc-1 antibody, encr-3 antibody, Nrpb antibody, ectodermal-neural cortex 1 antibody, ectodermal-neural cortex 1 (with BTB domain) L homeolog antibody, ENC1 antibody, enc1 antibody, enc1.L antibody, Enc1 antibody
- 背景
- DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53, MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50 % of all tumors. Polyak et al. (1997) [PubMed 9305847] used serial analysis of gene expression (SAGE) to evaluate cellular mRNA levels in a colorectal cancer cell line transfected with p53. Of 7,202 transcripts identified, only 14 were expressed at levels more than 10-fold higher in p53-expressing cells than in control cells. Polyak et al. (1997) [PubMed 9305847] termed these genes 'p53-induced genes,' or PIGs, several of which were predicted to encode redox-controlling proteins. They noted that reactive oxygen species (ROS) are potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. The authors stated that the PIG10 gene, also called ENC1, encodes an actin-binding protein.
- 分子量
- 66130
- 基因ID
- 8507
- NCBI登录号
- NP_001243503, NP_001243504, NP_001243505, NP_003624
- UniProt
- O14682
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