CDK5R1 抗体 (C-Term)
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- 抗原 See all CDK5R1 抗体
- CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
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抗原表位
- AA 272-301, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK5R1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B, M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CDK5R1(p35) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human CDK5R1(p35).
- 克隆位点
- RB36667
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CDK5R1 Primary Antibody
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anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 208-307) antibody
CDK5R1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) antibody (HRP)CDK5R1 适用: 人 WB, ELISA, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal JJ6 HRP
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) antibody (Alkaline Phosphatase (AP))CDK5R1 适用: 人 WB, ELISA, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal JJ6 Alkaline Phosphatase (AP)
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) antibody (Biotin)CDK5R1 适用: 人 WB, ELISA, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal JJ6 Biotin
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) antibody (APC)CDK5R1 适用: 人 WB, ELISA, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal JJ6 APC
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) antibody (Atto 390)CDK5R1 适用: 人 WB, ELISA, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal JJ6 Atto 390
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (N-Term) antibodyCDK5R1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (N-Term) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (Tyr579) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 99-307) antibodyCDK5R1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
- 别名
- CDK5R1(p35) (CDK5R1 产品)
- 别名
- CDK5P35 antibody, CDK5R antibody, NCK5A antibody, p23 antibody, p25 antibody, p35 antibody, p35nck5a antibody, cdk5r1 antibody, zgc:92814 antibody, CDK5R1 antibody, Cdk5r antibody, P25/P35 antibody, D11Bwg0379e antibody, Xp35.1 antibody, cyclin dependent kinase 5 regulatory subunit 1 antibody, cyclin-dependent kinase 5, regulatory subunit 1b (p35) antibody, cyclin-dependent kinase 5 regulatory subunit 1 antibody, S100 calcium binding protein A9 antibody, cyclin-dependent kinase 5, regulatory subunit 1 (p35) antibody, cyclin-dependent kinase 5, regulatory subunit 1 (p35) L homeolog antibody, CDK5R1 antibody, cdk5r1b antibody, Cdk5r1 antibody, S100A9 antibody, cdk5r1.L antibody
- 物质类
- Viral Protein
- 背景
- P35 is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5), the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. The p25 form accumulates in the brain neurons of patients with Alzheimer's disease. This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimer's disease.
- 分子量
- 34060
- 基因ID
- 8851
- NCBI登录号
- NP_003876
- UniProt
- Q15078
- 途径
- Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
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