GLP1R 抗体 (AA 101-150)
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北京 101111
Quick Overview for GLP1R 抗体 (AA 101-150) (ABIN1535693)
抗原
See all GLP1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-150
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原理
- GLP-1R Antibody
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特异性
- GLP-1R Polyclonal Antibody detects endogenous levels of GLP-1R protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GLP1R. AA range:101-150
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
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别名
- GLP1R
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背景
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Synonyms: GLP1R, Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, GLP-1R
Background: glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],
Gene Name: GLP1R
Protein Name: Glucagon-like peptide 1 receptor
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分子量
- 53 kDa
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基因ID
- 2740
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OMIM
- 138032
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UniProt
- P43220
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
抗原
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