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GLP1R 抗体 (AA 101-150)

The 兔 多克隆 anti-GLP1R antibody (ABIN1535693) specifically detects GLP1R in WB, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1535693
发货至: 中国
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Quick Overview for GLP1R 抗体 (AA 101-150) (ABIN1535693)

抗原

See all GLP1R 抗体
GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

适用

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人, 小鼠, 大鼠

宿主

  • 48
  • 4
  • 2
  • 2
  • 1
兔

克隆类型

  • 49
  • 8
多克隆

标记

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This GLP1R antibody is un-conjugated

应用范围

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  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 9
    • 4
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    • 2
    • 2
    • 2
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    • 1
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    AA 101-150

    原理

    GLP-1R Antibody

    特异性

    GLP-1R Polyclonal Antibody detects endogenous levels of GLP-1R protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GLP1R. AA range:101-150

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

    别名

    GLP1R

    背景

    Synonyms: GLP1R, Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, GLP-1R

    Background: glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],

    Gene Name: GLP1R

    Protein Name: Glucagon-like peptide 1 receptor

    分子量

    53 kDa

    基因ID

    2740

    OMIM

    138032

    UniProt

    P43220

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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