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GLP1R 抗体 (AA 22-116)

GLP1R 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6141138
发货至: 中国
  • 抗原 See all GLP1R 抗体
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    抗原表位
    • 16
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-116
    适用
    • 47
    • 42
    • 26
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 53
    • 2
    • 2
    • 1
    克隆类型
    • 56
    • 2
    多克隆
    标记
    • 28
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLP1R antibody is un-conjugated
    应用范围
    • 41
    • 20
    • 19
    • 13
    • 13
    • 13
    • 11
    • 9
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    GPRPQGATVS LWETVQKWRE YRRQCQRSLT EDPPPATDLF CNRTFDEYAC WPDGEPGSFV NVSCPWYLPW ASSVPQGHVY RFCTAEGLWL QKDNS
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 22-116 of human GLP1R (NP_002053.3).
    亚型
    IgG
    Top Product
    Discover our top product GLP1R Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Gao, Li, Li: "Exendin-4 promotes the osteogenic differentiation of osteoblasts via the Hedgehog/Gli1 signaling pathway." in: American journal of translational research, Vol. 10, Issue 1, pp. 315-324, (2018) (PubMed).

  • 抗原
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    别名
    GLP1R (GLP1R 产品)
    别名
    GLP1R antibody, LOC100228311 antibody, GLP-1R antibody, GLP1Rc antibody, Glip antibody, RATGL1RCP antibody, glucagon like peptide 1 receptor antibody, glucagon-like peptide 1 receptor antibody, GLP1R antibody, Glp1r antibody
    背景
    This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.,GLP1R,GLP-1,GLP-1-R,GLP-1R,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Neuroscience,Cardiovascular,GLP1R
    分子量
    53 kDa
    基因ID
    2740
    UniProt
    P43220
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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