Adenosine A2a Receptor 抗体 (AA 120-169)
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Quick Overview for Adenosine A2a Receptor 抗体 (AA 120-169) (ABIN1535559)
抗原
See all Adenosine A2a Receptor (ADORA2A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-169
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原理
- Adenosine A2A-R Antibody
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特异性
- Adenosine A2A-R Polyclonal Antibody detects endogenous levels of Adenosine A2A-R protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ADORA2A. AA range:120-169
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Adenosine A2a Receptor (ADORA2A)
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别名
- ADORA2A
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背景
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Synonyms: ADORA2A, ADORA2, Adenosine receptor A2a
Background: adenosine A2a receptor(ADORA2A) Homo sapiens This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript compos
Gene Name: ADORA2A
Protein Name: Adenosine receptor A2a
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分子量
- 44 kDa
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基因ID
- 135
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OMIM
- 102776
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UniProt
- P29274
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途径
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints
抗原
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