PCNA 抗体 (AA 61-110)
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北京 101111
Quick Overview for PCNA 抗体 (AA 61-110) (ABIN1533376)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-110
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原理
- PCNA Antibody
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特异性
- PCNA Polyclonal Antibody detects endogenous levels of PCNA protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PCNA. AA range:61-110
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:100-500,IF ICC 1:100-500,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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别名
- PCNA
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背景
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Synonyms: PCNA, Proliferating cell nuclear antigen, PCNA, Cyclin
Background: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],
Gene Name: PCNA
Protein Name: Proliferating cell nuclear antigen
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分子量
- 28 kDa
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基因ID
- 5111
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OMIM
- 176740
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UniProt
- P12004
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途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
抗原
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