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Connexin 43/GJA1 抗体 (AA 333-382)

The 兔 多克隆 anti-Connexin 43/GJA1 antibody is suitable to detect Connexin 43/GJA1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1533240
发货至: 中国
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Quick Overview for Connexin 43/GJA1 抗体 (AA 333-382) (ABIN1533240)

抗原

See all Connexin 43/GJA1 (GJA1) 抗体
Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

适用

  • 164
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人, 大鼠, 小鼠

宿主

  • 160
  • 10
  • 3
  • 1
  • 1
兔

克隆类型

  • 162
  • 12
多克隆

标记

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  • 1
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This Connexin 43/GJA1 antibody is un-conjugated

应用范围

  • 130
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  • 17
  • 14
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  • 9
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  • 7
  • 5
  • 2
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 35
    • 16
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    • 11
    • 9
    • 8
    • 8
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    • 7
    • 4
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    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 333-382

    原理

    Connexin 43 Antibody

    特异性

    Connexin 43 Polyclonal Antibody detects endogenous levels of Connexin 43 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Connexin 43. AA range:333-382

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

    别名

    Connexin 43

    背景

    Synonyms: GJA1, GJAL, Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein

    Background: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014],

    Gene Name: GJA1

    Protein Name: Gap junction alpha-1 protein

    分子量

    43 kDa

    基因ID

    2697

    OMIM

    121014

    UniProt

    P17302

    途径

    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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