CSNK1A1 抗体 (AA 287-336)
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Quick Overview for CSNK1A1 抗体 (AA 287-336) (ABIN1532765)
抗原
See all CSNK1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 287-336
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原理
- Casein Kinase Iα Antibody
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特异性
- Casein Kinase Iα Polyclonal Antibody detects endogenous levels of Casein Kinase Iα protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CKI-alpha. AA range:287-336
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亚型
- IgG
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应用备注
- Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
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别名
- CKI-alpha
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背景
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Synonyms: CSNK1A1, Casein kinase I isoform alpha, CKI-alpha, CK1
Background: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma(IKBKG) Homo sapiens This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016],
Gene Name: CSNK1A1
Protein Name: Casein kinase I isoform alpha
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分子量
- 38 kDa
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OMIM
- 600505
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UniProt
- P48729
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途径
- WNT signaling, Hedgehog Signaling
抗原
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