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BAX 抗体 (pSer184)

Cited in 1 publication. This anti-BAX antibody is a 兔 多克隆 antibody detecting BAX in IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1532125
发货至: 中国
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Quick Overview for BAX 抗体 (pSer184) (ABIN1532125)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAX antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 143-192, pSer184

    特异性

    Bax (Phospho-Ser184) Antibody detects endogenous levels of Bax only when phosphorylated at Ser184.

    PhosphorylationH:S184 M:S184 R:S184

    纯化方法

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184.

    亚型

    IgG
  • 应用备注

    IHC: 1:50~1:100 ELISA: 1:10000

    说明

    Unigene-Number: Hs.433670, Hs.631546 (NCBI Gene Symbol: BAX)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable at -20°C for at least 1 year.

    有效期

    12 months
  • Berger, Quast, Plötz, Kammermeier, Eberle: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." in: Cell death & disease, Vol. 4, pp. e477, (2013) (PubMed).

  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    Bax

    背景

    Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4 , BAX , BCL2L4

    NCBI Gene Symbol: BAX

    分子量

    21 kDa

    基因ID

    581

    OMIM

    600040

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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