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PAK2 抗体 (pSer141)

This 兔 多克隆 antibody specifically detects PAK2 in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1532070
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PAK2 抗体 (pSer141) (ABIN1532070)

抗原

See all PAK2 抗体
PAK2 (P21-Activated Kinase 2 (PAK2))

适用

  • 114
  • 65
  • 63
  • 4
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 109
  • 5
兔

克隆类型

  • 88
  • 26
多克隆

标记

  • 62
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PAK2 antibody is un-conjugated

应用范围

  • 79
  • 55
  • 53
  • 31
  • 22
  • 21
  • 10
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 14
    • 12
    • 11
    • 11
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-156, pSer141

    原理

    PAKγ (phospho Ser141) Antibody

    特异性

    Phospho-PAKγ (S141) Polyclonal Antibody detects endogenous levels of PAKγ protein only when phosphorylated at S141.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human PAK2 around the phosphorylation site of Ser141. AA range:107-156

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PAK2 (P21-Activated Kinase 2 (PAK2))

    别名

    PAK2

    背景

    Synonyms: PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58

    Background: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities.The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],

    Gene Name: PAK2

    Protein Name: Serine/threonine-protein kinase PAK 2

    分子量

    58 kDa

    基因ID

    5062

    OMIM

    605022

    UniProt

    Q13177

    途径

    MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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